Comments on: Cell therapy clinical trials 2009 – part III

By: Alex

Alex — Mon, 07 Sep 2009 21:09:49 +0000

Thanks Mohan, Yes it was great study. I highlighted it in 2nd issue of "cell Therapy clinical trials 2009".

By: Mohan C. Vemuri

Mohan C. Vemuri — Fri, 04 Sep 2009 21:22:28 +0000

Alex – really great job.

A recent publication in JAMA (April 15, 2009)highlighted on clinical trail results on Type 1 diabetes mellitus, following autologous nonmyeloablative Hematopoietic Stem cell transplantation, in 29.8 month follow up study. This study achieved insulin independence as well the patients achieved significant C-peptide levels. It might be a worth addition to Alex’s compiled list

By: Alex

Alex — Thu, 27 Aug 2009 13:13:37 +0000

I’d agree in general.
Unfortunately results from different groups frequently different. So, we don’t have many conclusive data, based on clinical trials results.
Recent findings from long-term follow-up fetal neurotransplantation is not good. Even most trials indicated short-term improvement.
Cancer vaccines also doing so so. Expectations a while ago were much greater then results we got.
Tolerance induction is sounds great!

By: Mr. Gunn

Mr. Gunn — Wed, 26 Aug 2009 19:20:35 +0000

Thanks for compiling this summary, Alexey. The tolerance induction work is pretty interesting, the cancer vaccine work is coming along, but the neural stuff still seems like it’s struggling to make significant headway. Would you agree?