http://hematopoiesis.info/2009/01/11/mapping-quiescence-of-hematopoietic-stem-cells/ Blood Stem Cell & Lineages Tue, 07 Sep 2010 01:58:45 +0000 http://wordpress.org/?v=abc hourly 1 http://hematopoiesis.info/2009/01/11/mapping-quiescence-of-hematopoietic-stem-cells/comment-page-1/#comment-10960 JWS Sun, 11 Jan 2009 20:38:23 +0000 http://hematopoiesis.info/2009/01/11/mapping-quiescence-of-hematopoietic-stem-cells/#comment-10960 Very good example of getting away from speculating about how hematopoietic stem cell works to actually confirming using experiments. This study was also possible because of new mouse models H2B-GFP, but this is just secondary. It was the way they interpreted the BrdU data (rather than assuming a single population, the kinetic curve shows double populations) that has opened up a new hypothesis and following investigations using complementary approaches, including H2B-GFP model. Very good example of getting away from speculating about how hematopoietic stem cell works to actually confirming using experiments. This study was also possible because of new mouse models H2B-GFP, but this is just secondary. It was the way they interpreted the BrdU data (rather than assuming a single population, the kinetic curve shows double populations) that has opened up a new hypothesis and following investigations using complementary approaches, including H2B-GFP model.

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